Fernandez RC, Moore VM, Rumbold AR, et al. - By conducting this cross-sectional study of a community-based cohort of 974 women, researchers investigated whether reproductive, metabolic or psychological health profiles of females with clinically diagnosed polycystic ovary syndrome (PCOS) vary from those with undiagnosed PCOS. Having experienced issues with periods (95%) and excess body hair (63%) were stated by a great majority of females with a prior diagnosis of PCOS. Corresponding proportions for females undiagnosed until study participation were noted to be slightly lower (81% and 45%, respectively). Obtaining a clinical diagnosis of PCOS was shown to be strongly associated with the experience of fertility issues, but not clinical depression or poor metabolic health, although a high prevalence of these was seen in females suffering from PCOS regardless of when they were diagnosed. These data strengthen the requirement for early identification of PCOS symptoms from adolescence, ensuring timely diagnosis as well as appropriate health care.