Yang YC, Wang JJ, Huang Y, et al. - Since ameloblastoma is a benign odontogenic neoplasm with a high local recurrence rate if the operation is not thorough, however, a useful clinical tool for the quantitative assessment of the prognosis and risk of postoperative recurrence of ameloblastoma has not yet been constructed, researchers sought to develop a prognostic nomogram model for ameloblastoma of the jaw to aid surgeons in surgical decision-making. Patients who underwent initial ameloblastoma surgery in the department between October 2004 and March 2020 were enrolled and randomly assigned to training and validation groups. In total, 302 eligible patients with ameloblastoma were selected, 54 of whom were confirmed to relapse during the follow-up period of 6 to 191 months. Four independent predictors, including cortical bone perforation, root(s) resorption, WHO classification, and treatment pattern, have been identified and involved in the construction of a nomogram for recurrence-free survival (RFS), which showed promising calibration performance and discrimination in the training set and the validation set. Based on individual characteristics, a favorable nomogram was developed that correctly predicted the RFS of patients with ameloblastoma. The nomogram-based risk stratification could improve tailored therapy and follow-up.