Oldham MA, et al. – In this prospective observational cohort study, researchers examined depression, mild cognitive impairment (MCI), and cerebrovascular disease as post-coronary artery bypass graft delirium risk factors. The study sample consisted of 131 subjects, and researchers found that age, MCI, and preoperative depression—but not lifetime depression—predicted delirium. In univariate analysis, middle cerebral artery (MCA) stenosis and severity predicted delirium but not in multivariate analysis. Right MCA stenosis severity but not left-sided stenosis severity predicted delirium severity. Overall, the authors concluded that delirium risk attributable to depression may extend beyond the influence of cognitive impairment and cerebrovascular disease alone.