Shah YS, Stroh IG, Zafar S, et al. - In this retrospective study, researchers sought to determine the prevalence and reasons for delays in diagnosis in patients with Acanthamoeba keratitis (AK) presenting to Wilmer Eye Institute, Baltimore, Maryland. All patients with culture‐positive AK seen at a tertiary referral centre between 2012 and 2019 were analyzed. Patient demographic information, clinical history, risk factors, symptom duration, referral patterns, slit lamp examination findings, visual acuity and need for surgery have been obtained. Participants in the study were 43 patients (45 eyes). Owing to a misdiagnosis such as herpetic keratitis, non‐specific clinical signs including the lack of pain in a number of patients, and a delay in referral to a tertiary care centre, delayed diagnosis of AK in the cohort occurred. Acanthamoeba cultures should be referred immediately to any contact lens wearer with atypical keratitis.