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Definitive intensity‐modulated radiotherapy or surgery for early oral cavity squamous cell carcinoma: Propensity‐score‐matched, nationwide, population‐based cohort study

Head & Neck Dec 16, 2020

Liu WC, Liu HE, Kao YW, et al. - In this propensity‐score‐matched, nationwide, population‐based cohort study, researchers estimated the outcomes of intensity‐modulated radiation therapy (IMRT) and surgery for patients with early oral cavity squamous cell carcinoma (E‐OCSCC). Patients from the Taiwan Cancer Registry Database who had received a diagnosis of E‐OCSCC were recruited. In the multivariate Cox regression analyses, the adjusted hazard ratio (aHR) for surgery compared with definitive IMRT, T2N0M0 compared with T1N0M0, and male patients vs female patients were 0.303 (0.245, 0.375), 1.340 (1.077, 1.668), and 2.012 (1.432, 2.826), respectively. Findings suggested that surgery can be considered the first choice rather than definitive IMRT for patients with E-OCSCC.

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