Beelen EMJ, van der Woude CJ, Janneke C, et al. - In Crohn disease (CD) patients, researchers conducted this nationwide cohort study to evaluate time trends in intestinal resection and re-resection. Adult CD patients with ileocolonic, small bowel, colon, or rectum resections between 1991 and 2015 were involved. Data from the Dutch nationwide network and registry of histopathology and cytopathology (PALGA) were collected. The cohort consisted of 8,172 CD patients (3,293/4,879 male/female) in whom 10,315 intestinal resections were conducted. It was noted that the annual intestinal resection rate was reduced in a nonlinear fashion from 22.7/100,000 CD patients (1991) to 2.5/100,000 (2015). Ileocolonic, small bowel, and colon resections had similar trends. For ileocolonic, small bowel, and colonic CD, intestinal resection rate has been reduced significantly over the past 25 years. In addition, there is a 75% lower chance of intestinal re-resection in current postoperative CD patients.