Lazenby GB, Savage AH, Horner G, et al. - As per reports, US cases of chlamydia and gonorrhea have increased since 2000, whereas decrease has been observed in the prevalence of these diseases in studies in select populations. Researchers here examined if there has been an increase in these diagnoses among pregnant women delivering at their center. Women delivering at least 1 infant > 18 weeks of gestation at the Medical University of South Carolina for 11 years (2008–2018) were included in this retrospective study. A total of 24,807 deliveries were performed during the study period. Among these, 5% of women were diagnosed with chlamydia and 1.2% with gonorrhea. Findings overall revealed a declining trend in diagnoses of chlamydia and gonorrhea among these pregnant women. Although a higher likelihood to have either diagnoses was observed among Black women delivering, a significant decline in both chlamydia and gonorrhea has occurred among them over time.