Trepka MJ, et al. – This research incorporated the analysis of the magnitude of deaths as a result of cancers for which screening recommendations existed, for people living with HIV in Florida. The significance of primary and secondary cancer prevention during primary care, for people living with HIV infection, was brought to the forefront during this study.

Methods

• Florida Department of Health Enhanced HIV/AIDS Reporting System data were matched with Department of Health Vital Records and the National Death Index.
• These aided in determining deaths and their causes through 2014.
• Estimation was performed of the sex-specific and cause-specific mortality rates and indirect standardized mortality ratios (SMRs, using U.S. mortality rates as a standard), during 2016 for people reported with HIV infection 2000-2014.

Results

• Regardless of the competing risk of HIV mortality, among the 25,678 females, there appeared to be a higher risk of cervical (SMR=6.32, 95% CI=4.63, 8.44), colorectal (SMR=2.05, 95% CI=1.44, 2.83), liver (SMR=8.96, 95% CI=5.39, 14.03), and lung (SMR=5.82, 95% CI=4.80, 6.96) cancer mortality and lower risk of breast cancer mortality (SMR=0.57, 95% CI=0.42, 0.76).
• Among 63,493 males, there was a higher risk of liver (SMR=5.50, 95% CI=4.47, 6.70) and lung (4.63, 95% CI=4.11, 5.19) cancer mortality.
• Among males, the lung cancer SMR considerably declined 2000-2014 (p<0.05).
• However, it remained high in 2012-2014 (SMR=3.59, 95% CI=2.87, 4.43).