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Death of a partner and risks of ischemic stroke and intracerebral hemorrhage: A nationwide Danish matched cohort study

Journal of the American Heart Association Nov 22, 2020

Fenger‐Grøn M, Møller IP, Pedersen HS, et al. - Using nationwide high‐quality register resources, researchers explored the connections between bereavement and ischemic stroke (IS) and intracerebral hemorrhage (ICH) separately in contemporary care settings. The sample consisted of all Danish people whose partner died between 2002 and 2016 and a reference group of cohabiting individuals matched 1:2 on sex, age, and calendar time. Two hundred seventy-eight thousand seven hundred fifty-eight individuals experienced partner bereavement during the study period, of whom 7,684 had an IS and 1,139 experienced an ICH within the following 5 years. For both IS and ICH risks, statistically significant positive correlations with partner bereavement were reported, especially for ICH in the short term. Absolute risk differences were, however, minimal. The estimated association for ICH tended to be stronger within the initial 30 days after partner death, particularly in women, but the statistical precision was low.

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