Ho Lee PC, et al. - The relationship between amelioration of hepatic dysfunction and improvement was investigated in various metabolic parameters among Chinese subjects with type 2 diabetes. Researchers found improvement in both the metabolic and hepatic dysfunction with dapagliflozin and empagliflozin as a class effect. Independent of body weight, the amelioration of hepatic dysfunction was mediated partly through an alleviation of hyperglycemia and possibly through an improvement in insulin resistance.