Mindikoglu AL, et al. - The gender differences were investigated in serum Cr, cystatin C, and other endogenous glomerular filtration rates (GFRs) biomarkers, measured and estimated GFR, Cr clearance, and Cr production rates in patients with cirrhosis. The outcomes recommended that cystatin C and endogenous GFR biomarkers other than Cr, measured GFR, GFR estimated by Cr–cystatin C GFR equation for cirrhosis, measured and estimated Cr clearance minimized between-gender biases in accounting for renal function in patients with cirrhosis. Therefore, when renal function was evaluated in patients with cirrhosis (particularly in women and those with sarcopenia) serum cystatin C ought to be measured as a complementary test to serum Cr.