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Current survival and treatment trends for surgically resected intrahepatic cholangiocarcinoma in the United States

Journal of Gastrointestinal Oncology Oct 01, 2018

Altman AA, et al. - Researchers assessed national trends in the surgical and medical management of patients with resected intrahepatic cholangiocarcinoma (ICC), and more specifically, the role of lymphadenectomy (LAD) and utilization of chemotherapy via analyzing an augmented version of the National Cancer Institute’s Surveillance, Epidemiology, and End Results cancer database registry. They identified 1,263 patients who underwent resection for ICC. Analysis of the treatment and outcomes of resectable ICC suggested that, at the time of surgical resection, lymph node evaluation remains inadequate, and the lack of LAD likely results in under-staging and underutilization of chemotherapy. Further, findings revealed an increasing trend in utilization of chemotherapy over time and a continuous improvement in median overall survival despite less than ideal surgical and medical therapy.

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