Vasconcellos HD, et al. - Using three-dimensional echocardiography (3DE), researchers investigated the link between cumulative blood pressure (BP) from young adulthood to middle age with left atrial (LA) structure/function. A prospective post hoc analysis was performed including individuals enrolled at the Coronary Artery Risk Development in Young Adults, a multi-center bi-racial cohort with 30 years of follow-up. Findings revealed adverse LA remodeling in association with higher cumulative BP from early adulthood throughout middle age.