Creatinine-to-cystatin C ratio as a marker of skeletal muscle mass in older adults: J-SHIPP study
Clinical Nutrition Aug 11, 2019
Tabara Y, et al. - In an elderly population aged ≥ 60 years, researchers examined the usefulness of creatinine-to-cystatin C ratio (CCR) in distinguishing the risk of low muscle mass and weak muscle strength. The study sample consisted of 1,329 apparently healthy community residents. Using computed tomography, the cross-sectional area (CSA) of muscle in the mid-thigh was measured. From each participant’s medical record, clinical data recorded at routine medical check-ups were obtained. According to findings, mean muscle CSA was 109 ± 24 cm2. CCR by quartiles according to sex was strongly linked to muscle CSA. In older community-dwelling adults, CCR was found to be a simple marker of low muscle mass and weak muscle strength.
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