Zhu Y, et al. – Efficacy and safety of remifentanil versus other opioids in mechanically ventilated patients, were assessed. Findings indicated that duration of mechanical ventilation, time to extubation after cessation of sedation, and length of ICU stay (ICU-LOS) appeared to be reduced in association with remifentanil use. In addition, hospital–LOS, costs, mortality or agitation offered by remifentanil versus other opioids did not vary significantly.