Fan S, et al. – A preliminary study was designed to evaluate whether dual energy computed tomography (CT) with iodine quantification is correlated with molecular markers Ki–67and hypoxia–inducible factor 1α (HIF–1 alpha)in rectal cancer (RC). The data showed that the normalized iodine concentration (NIC) values on dual energy computed tomography may be applied as a measurement of hypoxia in RC and determining the ability of tumor invasion noninvasively.