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Coronary plaque characteristics and epicardial fat tissue in long term survivors of type 1 diabetes identified by coronary computed tomography angiography

Cardiovascular Diabetology May 09, 2019

Svanteson M, et al. - In patients with type 1 diabetes mellitus (T1DM) for ≥ 45 years (n=88), researchers evaluated coronary atherosclerosis, plaque morphology as well as correlations to cardiovascular risk factors and epicardial adipose tissue (EAT). This study also included 60 controls. All the participants underwent coronary CT angiography (CCTA). Findings revealed a higher prevalence of coronary atherosclerosis among long-term survivors of T1DM vs controls. A protective impact on coronary atherosclerosis was shown by low low-density lipoprotein cholesterol and glycated hemoglobin over time. No link was evident between EAT volume and coronary atherosclerosis in T1DM patients.

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