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Contrast-induced nephropathy is associated with new-onset atrial fibrillation in acute coronary syndrome after cardiac catheterization: Systemic review and meta-analysis

Annals of Noninvasive Electrocardiology Jan 12, 2019

Prasitlumkum N, et al. - Whether contrast-induced nephropathy (CIN) is related to new-onset atrial fibrillation (AF) in patients with acute coronary syndrome (ACS) was investigated by analyzing evidence from cohort studies that compared new-onset AF after cardiac catheterization in ACS patient with CIN vs without CIN. These studies were identified via comprehensive search of databases of MEDLINE and EMBASE from inception to April 2018. Meta-analysis was performed including five studies from December 2009 to February 2018, involving 5,640 subjects with ACS (1,102 with CIN and 4,538 without CIN). Findings revealed that, CIN was linked to threefold increased odds of new-onset AF among patients with ACS following cardiac catheterization (pooled risk ratio = 2.84, 95% confidence interval: 1.66–4.87, p < 0.001, I2 = 58%).

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