Negishi Y, et al. - Given an increase in the incidence of contrast-induced nephropathy (CIN) with the progression of renal dysfunction and the recent evidence that percutaneous coronary intervention (PCI) can be safely performed even in patients with advanced renal dysfunction by appropriate CIN-prevention strategies, researchers examined the data of 323 consecutive patients with advanced renal dysfunction (eGFR<30 mL/min/1.73m²) who underwent PCI at five hospitals to assess the occurrence and prognostic influence of CIN. Outcomes revealed the incidence of CIN in Japanese patients with advanced renal dysfunction in routine clinical practice was not high. While the studied population had poor long-term prognosis following PCI, CIN had no significant prognostic value.