van Eekelen E, et al. - In this cross-sectional analysis that included a population-based cohort of middle-aged men and women, researchers assessed the intake of alcoholic and nonalcoholic beverages and their mutual replacement in relation to hepatic triglyceride content (HTGC). Overall 1,966 subjects were included (mean ± SD age of 55 ± 6 years, BMI of 26 ± 4 kg/m², and HTGC of 5.7% ± 7.9%, which was evaluated by proton magnetic resonance spectroscopy). They used a validated food-frequency questionnaire to determine habitual intake of alcoholic and nonalcoholic beverages. Findings revealed a link between the consumption of each extra daily alcoholic beverage and more liver fat. In isocaloric replacement of alcoholic beverages, less liver fat was detected in relation to milk whereas sugar-sweetened beverages were equally related to liver fat. Overall, these findings were suggestive of a possible contribution of alcohol and sugar intake to liver fat accumulation.