Consequences of a recent past dengue infection for acute and long-term chikungunya outcome: A retrospective cohort study in Curaçao
Travel Medicine and Infectious Disease Apr 05, 2018
Elsinga J, et al. - The acute and long-term clinical presentation patterns of chikungunya against a backdrop of preceding dengue infection were investigated and predicting factors for long-term chikungunya sequelae were determined. Patients with chikungunya and a preceding dengue infection were assessed as having more myalgia and arthritis. Acute chikungunya (without preceding dengue) presented more often with cough when compared to chikungunya with recent dengue. Compared to other studies on acute chikungunya disease presentation, this study reported similar proportions of fever, arthralgia and rash while myalgia and headache were reported in higher proportions. This study also identified age, co-morbidity (joint disease and cardiovascular disease) and female sex as predicting factors for longer or worse disease outcome.
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