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Congenital hearing loss is associated with a high incidence of central nervous system abnormalities

Otology & Neurotology Nov 18, 2020

Sayyid ZN, Boldt B, Mokhtari TE, et al. - Researchers investigated pediatric patients with sensorineural hearing loss (SNHL) in order to determine the incidence of central nervous system abnormalities in this group of patients. This analysis involved 143 children assessed for SNHL at a single academic center from 2007 to 2014, split into eight diagnosis categories depending on etiology of SNHL. Healthy controls, 143 age- and gender-matched controls with no known brain-related pathology or history of hearing loss, were also included. A high incidence of intracranial abnormalities was identified on magnetic resonance imaging (MRI), indicative of aberrant development of auditory and nonauditory neural structures related to SNHL. For identifying temporal bone anomalies, computed tomography and MRI shared a high degree of concordance. The identification of developmental anomalies of the brain related to SNHL may be facilitated by incorporation of MRI as a component of the workup of congenital SNHL.

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