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Computed tomography derived predictors of permanent pacemaker implantation after transcatheter aortic valve replacement: A meta‐analysis

Catheterization and Cardiovascular Interventions Jun 07, 2021

Maier O, Piayda K, Afzal S, et al. - A meta-analysis was conducted to explore predictors of permanent pacemaker implantation (PPI) after transcatheter aortic valve replacement (TAVR) with focus on preprocedural multi-slice computed tomography (MSCT) derived data. Researchers carried out a literature search in PubMed/MEDLINE and EMBASE databases to distinguish studies that evaluated preprocedural MSCT data and the rate of PPI following TAVR with new-generation devices. For the final analysis, ten observational studies including a total of  2,707 individuals were enrolled. Furthermore, PPI was conducted in 387 patients (14.3%) after TAVR. Besides the well-known impact of electrocardiographic and procedure-related factors on conduction disturbances, it has been reported that MSCT derived distribution of the aortic valve and left ventricular outflow tract calcification, as well as membranous septum length, are correlated with an elevated risk of PPI following TAVR.

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