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Comparison of the efficacy of different analgesia treatments for total knee arthroplasty: A network meta-analysis

The Clinical Journal of Pain Oct 11, 2018

Dong P, et al. - Researchers performed a comparison of the efficacy of several clinical treatments [patient-controlled epidural analgesia+femoral nerve block (FNB), sciatic nerve block, continuous femoral nerve block (cFNB), periarticular infiltration, periarticular infiltration+FNB, single-dose FNB, and sciatic nerve block+FNB] for postoperative analgesia of total knee arthroplasty (TKA) through network meta-analysis based on multiple published randomized controlled trials. In this network meta-analysis, they included a total of 58 studies with 3501 patients and selected pain score, morphine consumption (milligrams), and length of hospitalization (day) as the endpoints. Findings suggested that for patients undergoing TKA, cFNB was potentially the most efficacious postoperative treatment considering both pain score and morphine consumption.
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