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Comparison of the age-adjusted and clinical probability-adjusted D-dimer to exclude pulmonary embolism in the ED

The American Journal of Emergency Medicine Apr 27, 2019

Sharif S, et al. - In this study, researchers reviewed data to evaluate the effectiveness and safety of using age-adjusted D-dimer interpretation, clinical probability-adjusted D-dimer interpretation, and a standard D-dimer approach to eliminate pulmonary embolism (PE) in emergency department (ED) patients. They tested 1,163 emergency patients for PE, among whom 1,075 were eligible for study inclusion. With age-adjusted, clinical probability-adjusted, and standard D-dimer approach, they excluded PE in 70.4%, 80.3%, and 68.9%, respectively. They observed the respective negative predictive values of 99.7%, 99.1%, and 100%, respectively.

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