Comparison of short-wavelength blue-light autofluorescence and conventional blue-light autofluorescence in geographic atrophy
British Journal of Ophthalmology Jun 09, 2018
Borrelli E, et al. - Researchers performed a systematic comparison of the intermodality and inter-reader agreement for two blue-light confocal fundus autofluorescence (FAF) systems. Imaging of 30 eyes (21 patients) with a diagnosis of geographic atrophy (GA) was performed using two confocal blue-light FAF devices: (1) Spectralis device with a 488 nm excitation wavelength (488-FAF); (2) EIDON device with 450 nm excitation wavelength and the capability for ‘colour’ FAF imaging including both the individual red and green components of the emission spectrum. Outcomes revealed a reproducible quantification of GA with the isolation of the red emission fluorescence component (REFC) from the 450-FAF images. This assessment demonstrated good comparability with that obtained with 488-FAF images.
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