Numasawa Y, et al. - Researchers used the J-PCI (Japanese percutaneous coronary intervention) registry to assess outcomes following percutaneous coronary intervention (PCI) in elderly patients, especially nonagenarians. Overall 562,640 PCI patients (≥60 years of age) were included from 1,018 Japanese hospitals, and of those, 10,628 patients (1.9%) were ≥90 years of age, including 6,780 (1.2%) with acute coronary syndrome (ACS) and 3,848 (0.7%) with stable coronary artery disease. Sexagenarians, septuagenarians, octogenarians, and nonagenarians were compared with respect to features and in-hospital outcomes. Compared with younger patients, older patients tended to be women and had a higher frequency of heart failure and chronic kidney disease, as well as a higher rate of in-hospital mortality, cardiac tamponade, cardiogenic shock after PCI, and bleeding complications necessitating blood transfusion. A greater risk of in-hospital death and bleeding was observed among older patients, especially nonagenarians, vs younger patients after PCI. In elderly patients undergoing PCI, risk for periprocedural complications might be attenuated with transradial intervention.