Mursaloğlu HH, Akın C, Yeğit CY, et al. - No superiority of IV and non-IV treatment regimens was identified to one another in the eradication of Pseudomonas aeruginosa (PA) and MRSA in patients with cystic fibrosis (CF).

• A single-center retrospective study of respiratory specimen cultures of 309 CF patients and eradication regimens between 2015-2019.

• Analysis was performed including 102 patients with PA isolations and 48 patients with MRSA.

• The groups did not exhibit any statistically significant difference with respect to eradication.

• Further, no significant correlation appeared between any of the clinical risk factors and eradication failure in PA and MRSA groups.

• In view of the cost-effectiveness and the treatment burden of IV treatments due to hospitalization and the need for IV access, non-parenteral eradication appears a better option.