Léon P, et al. - Authors compared the ability of the cell cycle progression (CCP) score and the expression of PTEN or Ki-67 to predict biochemical recurrence (BCR) in a cohort of prostate cancer(PCa) patients treated by radical prostatectomy (RP). They constructed the best predictive model for BCR, incorporating biomarkers and relevant clinical variables. Researchers noted superiority of the CCP score to the 2 IHC markers (PTEN and Ki-67) for predicting outcome in PCa after RP. Out of the 3 biomarkers, a significant association of the CCP score in a multivariable Cox model was seen. The best model incorporated CAPRA-S and CCP scores as predictors, with HRs of 1.32 and 1.24, respectively.