Yu S, et al. - Considering a recent study suggesting upstroke time per cardiac cycle (UTCC) in lower extremities is equivalent to ankle-brachial index (ABI) in diagnosing peripheral arterial disease (PAD) and predicting cardiovascular mortality, researchers compared ABI and UTCC in relation to target organ damage (TOD). Researchers assessed 1,841 elderly participants from the Northern Shanghai Study. Findings reveal a significant association of upstroke time with most traditional CV risk factors. UTCC vs ABI was noted to be superior in discriminating target organ damage, suggesting that upstroke time could be useful for diagnosing PAD and stratifying CV risk.