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Comparison of 5-year safety and efficacy of laser photocoagulation and intravitreal bevacizumab injection in retinopathy of prematurity

Graefe's Archive for Clinical and Experimental Ophthalmology Mar 27, 2021

Murakami T, Sugiura Y, Okamoto F, et al. - Researchers conducted the study for comparing laser photocoagulation and intravitreal injection of bevacizumab (IVB) treatment for retinopathy of prematurity (ROP). The sample consisted of 26 patients (52 eyes) after ROP treatment who were observed up to 5 years of age. Twenty-eight eyes were treated with laser photocoagulation as the initial treatment (laser group), and twenty-four eyes were treated with IVB (IVB group). IVB was not inferior to laser for ROP in terms of neurodevelopment or visual outcome, and it was superior in terms of refractive error. Due to the presence of retinal holes in the IVB group, long-term follow-up with fundus examination is advised following IVB.

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