Mawardi P, Febrianto B, Yuliarto D, et al. - Coinfection with HIV is frequently observed in patients with condyloma acuminata (CA), a sexually transmitted infection caused by human papillomavirus (HPV), this is particularly noted in those with low CD4+ levels. Researchers performed a comparison of the efficacy of two therapeutic modalities for CA (chemical cautery and cryosurgery) on CD4+ status of HIV patients with CA.

• Chemical cautery and cryosurgery are aimed to remove lesions and prevent recurrence.

• A cross-sectional retrospective study was performed including 78 patients with CA (68% male).

• Of patients, 41 had HIV infection.

• Chemical cautery was used in managing 70.5% of the patients, and the remaining had cryosurgery.

• Both the therapeutic modalities were effective in improving the clinical condition of patients with CA.

• Although there was a higher level of CD4+ following chemical cautery vs cryosurgery, no statistically significant difference regarding CD4+ status was observed following the two therapies.