Sidney S, et al. - Authors analyzed differences between the U.S. and Kaiser Permanente Northern California (KPNC), a large integrated healthcare delivery system, with regard to recent trends in heart disease, stroke, and total mortality. There were notable declines in heart disease, stroke, coronary heart disease and all-cause mortality, with more drastic declines in the 45-65 age group within KPNC vs the U.S. This research highlights, in part, how effective high-quality, coordinated, age-specific cardiovascular risk management programs are and encourage their use in the vulnerable middle-aged population.