Semeraro F, et al. - Experts assessed the inflammation-related to the use of standard silicone oil (polydimethylsiloxane; PDMS) and heavy silicone oil (HSO) Densiron-68 in patients undergoing vitrectomy for retinal detachment. Nonetheless, in the surgical treatment of complicated retinal detachments, favourable success rates were yielded by both HSO and PDMS, a more severe inflammatory reaction was triggered by HSO in a time-dependent manner. In PDMS, the endotamponade duration was correlated in a strong positive manner with both PGE2 and IL-1α levels.