Del Giorno R, et al. - A retrospective cross-sectional study is done to research the following: 1) the long-term effect of hemodialysis (HD) treatment on platelet (PLT) count, comparing two families of dialysis membranes made up of similar PSfs; 2) whether the switch between the dialysis membranes studied significantly influences PLT count; and 3) the prevalence and the risk of HD-induced thrombocytopenia according to the dialysis membranes utilized. This information recommends that among the PSf membranes studied, the FX membrane induced a lasting decrease in PLT count and caused significantly more thrombocytopenia. Prospective examinations are justified to check these outcomes.