Dieu A, Van Regemorter V, Detaille T, et al. - In this subgroup analysis of a randomized clinical trial, researchers assessed Multiplate combined with Rotem in terms of guiding platelet transfusion following pediatric cardiac surgery with cardiopulmonary bypass (CPB). Also, they compared cyanotic and acyanotic patients in terms of coagulation parameters. Patients weighing between seven and 15 kg were included. At three time points Rotem and Multiplate tests were conducted: (1) following anesthesia induction, (2) upon CPB separation, and (3) upon intensive care unit arrival. Of 59 individuals, 9 patients needed platelet transfusion. As per findings, Rotem, but not Multiplate results, were related to platelet transfusion in pediatric cardiac surgery with no consumption of platelet inhibitors. The benefit of integrating these tests in platelet transfusion decision-making requires to be assessed in larger populations. Experts noted that platelet count and function did not differ significantly between groups of acyanotic and cyanotic heart disease patients. Significantly higher postoperative blood loss was noted in the cyanotic group vs the acyanotic arm.