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Combination therapy of rituximab and mycophenolate mofetil in childhood lupus nephritis

Pediatric Nephrology Aug 09, 2017

Hogan J, et al. – An analysis was formulated to gauge the impact of combination therapy of rituximab and mycophenolate mofetil (MMF) in childhood lupus nephritis (LN). As per the observations, therapy with rituximab (RTX) + MMF combined with a rapid decrease in steroid appeared as an efficacious treatment for severe LN. However, it was associated with high rate of varicella–zoster virus (VZV) infection.
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