Giorgio CM, Babino G, Caccavale S, et al. - Since alopecia areata (AA) is a complex, difficult-to-treat immune-mediate disorder, researchers tested a new therapeutic option for moderate to severe AA based on the combination of photodynamic therapy (PDT) with 5‐aminolaevulinic acid (ALA) and microneedling (MN). Participants (n = 14) in the study were randomly divided into three groups: Group A (MN alone; n = 9), Group B (ALA‐PDT alone; n = 15) and Group C (combination of MN and ALA‐PDT; n = 17). Findings indicate that combining ALA‐PDT with MN might be an additional therapeutic choice in moderate to severe AA, as MN allows better skin penetration of ALA and subsequent indirect immunosuppression.