Shafrir A, et al. - In this study conducted at a gastroenterology institute within an academic medical center, researchers compared 128 participants aged > 90 years vs 218 participants aged 80-89 years who underwent colonoscopy to determine the yield, safety, and therapeutic benefits of colonoscopy. In all, they noted that nonagenarians were more inclined to undergo a colonoscopy while hospitalized (56.2% vs 23.4%) and due to rectal bleeding or sigmoid volvulus (35.2% vs 25.2% and 10.9% vs 0.5%, respectively) vs for surveillance or constipation. They recorded the 30-day mortality rates as 3.9% among nonagenarians and 0.4% for octogenarians. They noted a greater incidence of advanced adenomas and carcinoma in nonagenarians. They also noted a relation of increasing age, inpatient status, past polypectomy surveillance, and anemia with higher rates of carcinoma. Overall, they concluded colonoscopy in nonagenarians to be safe and with a high yield.