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Cold platelets for trauma-associated bleeding: Regulatory approval, accreditation approval, and practice implementation--Just the "tip of the iceberg"

Transfusion Sep 18, 2017

Stubbs JR, et al. - Authors focus on cold platelets for trauma-associated bleeding. Ease of prehospital use plus potential hemostatic superiority led their facility to pursue approval of cold-stored platelets (CS-PLTs) for actively bleeding trauma patients. In the future, pathogen-reduced (PR), PLT additive solution (PAS) CS-PLTs appear more practical due to low risks of bacterial contamination and storage-related clotting. This should make longer storage of CS-PLTs feasible (e.g., 10 days or more). With a longer shelf life, PR PAS CS-PLTs have potential to be used in a wider range of patient populations.
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