Jee YH, et al. - Via conducting a population-based Korean cohort study on 481,355 Koreans (260,695 men and 220,660 women) aged 40–80 years, researchers examined the role of depression with respect to increasing the risk of developing atherosclerotic cardiovascular disease (ASCVD). Increase in the risk of ASCVD development by 41% in men and 48% in women was caused by depression. Three to four outpatient visits for depression also elevated the risk of angina pectoris and acute myocardial infarction in men. An association of depression with stroke in men and in women was also noted. Although, in comparison to those without any outpatient visit for depression, men who received 10 or more depressive treatments had no elevation in the risk of ASCVD. Therefore, increased risk of ASCVD incidence was only evident among patients with depression. Thus, routine monitoring of heart health for the prevention of future cardiovascular disease risk might be needed for this population.