Cognitive function deficits associated with long-duration type 1 diabetes and vascular complications
Diabetes Care Jun 09, 2018
Musen G, et al. - Given that patients with type 1 diabetes during middle age show mild cognitive deficits, researchers investigated whether severity increases with aging or whether cognitive profiles were similar to those of age-matched peers with and without diabetes. For this analysis, cognition in 82 individuals with 50 or more years of type 1 diabetes (Medalists), 31 age-matched individuals with type 2 diabetes, and 30 age-matched control subjects without diabetes were tested and compared. Findings revealed that both type 1 and type 2 diabetic patients exhibited overall worse cognition than control subjects. A relationship between complications and cognition was seen in Medalists. The underlying mechanisms might be different although both groups with diabetes showed similar deficit patterns. Outcomes suggested that endeavors ought to be made to assess cognition and to identify modifying behaviors to slow decline.
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