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Cognitive decline in older patients with non-ST elevation acute coronary syndrome

Journal of the American Heart Association Feb 21, 2019

Gu SZ, et al. – In this study involving 298 participants, researchers examined the prevalence of cognitive impairment and the predictors of cognitive deterioration at 1 year in older adults with non-ST–elevation acute coronary syndrome undergoing invasive care. Death, myocardial infarction, unplanned revascularization, stroke, and significant bleeding at 1 year comprised the composite major adverse cardiovascular events. A total of 271 participants had cognitive assessment at baseline, and 211 had follow-up Montreal Cognitive Assessment at 1 year. A high prevalence of undiagnosed cognitive impairment (Montreal Cognitive Assessment score of < 26) was recorded at baseline. After adjustment for age and sex, recurrent myocardial infarction was independently linked to cognitive decline at 1 year.

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