Zarbo C, Brugnera A, Dessì V, et al. - Researchers examined how personality traits and coping strategies influence pain experience in women with endometriosis. In this mixed-method sequential explanatory study composed of a quantitative survey followed by qualitative interviews, 162 women with endometriosis who completed a battery of validated questionnaires were included in the first quantitative phase. After statistical analysis, they developed a semistructured qualitative interview and conducted it with 6 of them, in order to help explain findings obtained in the first phase. As per the metamatrix, women with endometriosis are mainly concerned regarding acute pain experience, fear of its occurrence, its unpredictability, and control difficulties. This sample frequently exhibited worry trait characteristics (ie, the need for control, anticipatory anxiety, intrusive worry thoughts) and maladaptive thoughts such as coping strategies (ie, self-blame, rumination, catastrophizing), which appear to have an indirect effect on pain experience. Indeed, the unsuccessful struggle in controlling pain leads to the development of negative thoughts/beliefs and feelings of powerlessness, which, in turn, result in psychological distress and higher pain experience.