Zamora-Ros R, et al. – In previous cellular and animal studies, researchers showed that coffee and tea constituents have several anti-carcinogenic activities, including against thyroid cancer (TC). This prompted investigators to examine this relationship in a large prospective study, which was conducted in the EPIC (European Prospective Investigation into Cancer and Nutrition) cohort involving 476,108 adult men and women. A full 748 first incident differentiated TC cases were identified during a mean follow-up of 14 years. The researchers found no association of coffee consumption (per 100 mL/day) either with total differentiated TC risk or with the risk of TC subtypes. Tea consumption (per 100 mL/day) was not related to the risk of total differentiated TC and papillary tumor, while a reverse association with follicular tumor risk was found; however, this association was based on a sub-analysis of a small number of cancer cases. The investigators concluded that coffee and tea intakes were not correlated with TC risk.