• Profile
Close

Clusters of comorbidities in idiopathic pulmonary fibrosis

Respiratory Medicine Jun 05, 2021

Prior TS, Hoyer N, Hilberg O, et al. - This research sought to comprehensively and prospectively evaluate comorbidities in a multicentre, real-world cohort of patients with idiopathic pulmonary fibrosis (IPF), including prespecified conditions of special interest and to examine clusters of comorbidities and analyze characteristics, disease course and mortality of the clusters. Researchers used several measurements, questionnaires, medications and medical history to evaluate comorbidities. Self-organizing maps were used to distinguish clusters of comorbidities and phenotypes characterized. Using mixed effects models, disease course was evaluated and mortality was assessed by using Cox regression. The study enrolled 155 IPF patients prospectively. In patients with IPF, multimorbidity is prevalent. The data demonstrate that four specific clusters of comorbidities may represent phenotypes in IPF. According to the findings, a trend towards faster decline in exercise capacity and dyspnea was found in patients with fewer comorbidities. In patients with IPF, increased knowledge of comorbidities facilitates prevention and treatment of comorbidities.

Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free or login with your existing account.
4 reasons why Doctors love M3 India
  • Exclusive Write-ups & Webinars by KOLs

  • Nonloggedininfinity icon
    Daily Quiz by specialty
  • Nonloggedinlock icon
    Paid Market Research Surveys
  • Case discussions, News & Journals' summaries
Sign-up / Log In
x
M3 app logo
Choose easy access to M3 India from your mobile!


M3 instruc arrow
Add M3 India to your Home screen
Tap  Chrome menu  and select "Add to Home screen" to pin the M3 India App to your Home screen
Okay