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Clinicopathological significance of miR-26, miR-107, miR-125b, and miR-203 in head and neck carcinomas

Oral Diseases Jun 15, 2018

González-Arriagada WA, et al. - Researchers analyzed the expression of miR-26, miR-107, miR-125b, and miR-203 in primary head and neck squamous cell carcinomas (HNSCC) with and without lymph node metastasis and their clinicopathological significance. For this analysis, the expression of microRNAs in primary HNSCC with lymph node metastasis and their matched lymph node, as well as primary tumors without metastasis, were determined by quantitative RT-PCR and analyzed with clinicopathological features and survival. Results of this study infer that miR-26 and miR-125b could be correlated with the progression and metastasis of HNSCC, and that miR-203 was linked with a more favorable prognosis.

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