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Clinicopathological significance of lymphocytic colitis/collagenous colitis in inflammatory bowel disease

Human Pathology Nov 14, 2019

Yuan L, et al. - A total of 27 people with a diagnosis of either ulcerative colitis (UC) or Crohn disease (CD) and lymphocytic colitis/collagenous colitis (LC/CC) were assessed and their clinical, endoscopic, and pathological peculiarities were analyzed in order to determine the association between these two disorders, ie, IBD and LC/CC. It was discovered that IBD individuals with initial presentation of LC/CC tend to happen in elderly age, with a quicker interval time and frequent active inflammation in initial LC/CC. Findings imply that LC/CC could be a spectrum of IBD as the primary presentation in a subset of elderly IBD people. On the other hand, IBD individuals could make LC/CC related to chronic mucosal injury many years following the onset of IBD (usually with > 10 years interval time when people are in remission phase), for which these two methods appear independent of each other.
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