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Clinicopathological features of BRCA1/2 mutation-positive breast cancer

Oncology Jun 10, 2021

Paik HJ, Jung YJ, Kim DI, et al. - This study was undertaken to explore the clinicopathological characteristics of BRCA1/2 mutation-positive breast cancer patients. Between March 2015 and February 2020, researchers retrospectively examined clinical data of 188 Korean breast cancer patients who underwent genetic testing of BRCA1/2 mutation at Pusan National University Yangsan Hospital. They distinguished the clinicopathological characteristics of breast cancer patients with BRCA1/2 gene mutations. It was shown that BRCA1 gene expression was highly correlated with triple-negative breast cancer. The results demonstrate that BRCA1/2 mutation did not have a poor prognosis regarding recurrence and death.

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