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Clinical spectrum and management options in Vogt-Koyanagi-Harada disease

Clinical Ophthalmology Aug 14, 2017

Lodhi SA, et al. – The clinical features, treatment options, and visual outcome of Vogt–Koyanagi–Harada (VKH) disease patients more than a 9–year period are depicted in this study. In this South Indian population, VKH–related uveitis is more common in the female gender. Posterior uveitis is the most common initial manifestation. Initial aggressive treatment with intravenous methyl prednisolone (IVMP), peribulbar long–acting corticosteroids, and immunosuppressives, avoiding side effects of systemic steroids, gives a good visual outcome without recurrences. Cases of unilateral VKH, found in six patients, are the initial manifestations in the natural course of the disease, which if managed aggressively at the acute stage prevents recurrence in the other eye.
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